About Prednisone: Prednisone is a corticosteroid drug, which aids in treating inflammation and swelling in various medical conditions. This drug is actually not in the activated form. In the liver, 11beta hydroxysteroid dehydrogenase converts this drug into its activated form, which is Prednisolone. The important application of Prednisone also occurs in some cases of cancer. This drug has been successfully used in the treatment of various diseases like chronic tuberculosis, asthma, rheumatic disorders, ulcerative colitis, adrenocortical insufficiency, Crohn's disease etc. The chemical formula of Prednisone is C21H26O5. This drug is administered orally in most cases. However, it can also be given inintramuscular and intravenous injections.
How Prednisone Works: The action of Prednisone is based on this drug's affinity to alpha and beta glucocorticoid receptors. Once the Prednisone drug is taken, it is converted to its activated metabolite form Prednisolone. This combines with the alpha and beta glucocorticoid receptors, which are found in variable amount in almost all the cells of the body. It then modifies the gene transcription of these cells by transforming the DNA in the cell nucleus of these areas. As a result, some proteins are synthesized and others are prevented from being synthesized in this case. Thus, Prednisone actively fights the root cause of inflammation.
How To Take Prednisone: INephrotic Syndrome: The dosage of Buy Prednisone in this case varies from 2 to 3 mg per kg per day. A maximum 80 mg limit is maintained in this case. This is followed for a period of 3 days - 28 days maximum. The dose is then reduced to 1.5 mg of Buy Prednisone Online Canada, which is administered for 4 weeks. Anti-inflammatory treatment: The dosage of Prednisone Canada in this case varies from 5 mg to 60 mg per day based on the efficacy and the severity of the inflammation. Asthma: The dosage of Buy Prednisone Online varies in asthma cases along with age. Generally, the dosage varies for 20 mg to 4 mg based on the age of the patient. The dose increases with age. Pediatric dose: The pediatric dose of Prednisone Online also remains as 2mg per kg per day in most cases.
Precautions And Side Effects Of Prednisone: Prednisone shows 30 severe and 571 moderate drug interactions levels. The drugs with which Prednisone reacts severely with smallpox vaccine, bupropion, Moxifloxacin, leflunomide, ciprofloxacin, etanercept, enoxacin, and ofloxacin. The drugs with which Buy Prednisone shows moderate interactions include drugs like ibuprofen, zidovudine, amphotericin b lipid complex, somatropin, quinapril, aspirin, caffeine, codeine, and magnesium salicylate. These moderate interactions can show some mild allergic reactions whereas the major interactions show severe allergic symptoms. In these cases, the doctor must be informed about the medical history of the patient before the actual treatment begins. Buy Prednisone Canada also shows interactions with certain diseases and medical conditions. These diseases and medical conditions are gastro- intestinal perforation, diabetes, thromboembolism, myopathy, liver disease, and scleroderma. Thus, the doctor must be informed in these cases and medical attention is needed in severe drug reactions of Buy Prednisone Online in most cases. The side effects seen in the case of Prednisone Canada are either allergic or severe. The allergic side effects include symptoms like issues with sleeping, sensing a whirling motion in the head region, increased appetitie, higher amounts of sweating, dyspepsia, mood changes and nervousness. Prednisone Online can also result in severe reactions like hunger loss, black stool discharges, alterations in menstrual periods, seizures, gloominess, diarrhea, giddiness, heightened sense of healthy-being, fever, body uneasiness, headache, increased eye strain, joint and muscle soreness, mood changes, muscle feebleness, behavior changes, prolonged sore throat, wimping of the face, severe nausea and vomiting.